Eternal Chest is a pickup in The Binding of Isaac, added in the Afterbirth DLC.

Requires a key to open.

Has the same contents as a Locked Chest.

Once opened, it will close itself after 2 seconds, generating new content, but after the first time it's been opened, it has a 25% chance to give nothing and stay open, making it no longer usable.

The chest will also stay open if it contains an item, making it its final payout.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this pickup for the previous Repentance version, check this page instead.

• Check out the pickup description on the external Isaac Wiki.