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▾Table of Contents▾
Box of Friends item
Box of Friends is an unlockable active item in The Binding of Isaac, added in the Afterbirth DLC.
Description
Adds a copy of each of Isaac's familiars for the duration of the current room.
If Isaac has no familiars, it will instead spawn a Demon Baby for the duration of the room.
If Isaac already has more than one copy of a familiar, only one additional copy of that familiar will be added.
Cannot copy Blue Flies/Spiders.
Cannot copy familiars with the uniquefamiliar tag.
Note
This page shows information as of the latest Repentance release.
To see latest up-to date information about this item for the new Repentance+ (Online Co-op) DLC, check this page instead.
How to unlock?
Defeat Ultra Greed as 
Lilith.
Item pools
Box of Friends can be found in the following item pools:
| Name | Weight |
|---|---|
| Shop |
1.0/1.0
|
| Greed Treasure Room |
1.0/1.0
|
| Crane Game |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| offensive | Can appear for  Tainted Lost. |
Special synergies
The following special synergies and interactions for Box of Friends have been documented.
| Mod | Item | Synergy |
|---|---|---|
| --- | Book of Virtues | Spawns black wisps in the middle ring. After creating a wisp, Box of Friends will also give temporary copies of all of Isaac's wisps, including any extra copies made by Box of Friends. |
* Note that not all possible synergies and interactions are listed here.
External links
- Check out the item description on the external Isaac Wiki.
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Mom's Pearls 
Car Battery 
The Wiz 
8 Inch Nails 
Incubus