Locust of Pestilence is an unlockable trinket in The Binding of Isaac, added in the Afterbirth+ DLC.

Upon entering an unexplored room, spawns a Green Locust that dies upon impact with enemies, dealing 2x Isaac's damage for the impact, and poisons the enemy, dealing Isaac's amount of damage for 2 ticks.

This page shows information as of the latest Repentance release.
To see latest up-to date information about this trinket for the new Repentance+ (Online Co-op) DLC, check this page instead.

Defeat Satan as Apollyon.

The following special synergies and interactions for Locust of Pestilence have been documented.

* Note that not all possible synergies and interactions are listed here.

• Check out the trinket description on the external Isaac Wiki.