Base game
- Isaac (Repentance+)
- Isaac (Repentance)
-
Mods (0 • hidden)
- 21 Trinkets
- A Bushel of Burdens & Blessings
- Alphabirth+
- Anathema
- Andromeda
- Arachna
- Ascension
- Bael
- Balatro Jokers
- Baphomet
- Basement Moon
- Battle Fantasy
- Becky
- Bedroom Expanded
- Benevolence
- Benighted Soul
- Beyond
- Birthcake
- Birthcake: Rebaked
- Boss Butch!
- Brown Shapiro's Addons
- Chocolate Mod
- Community Remix
- Curiosity Crate
- D!Edith
- Damnation
- Dark Vaults
- David Pack
- Daydream all Day
- Doki Doki
- Eclipsed
- Elitium
- ENA Mod
- Ephemera
- Epiphany
- Fiend Folio
- Foks' Booster Pack
- Fruity Rooms
- Furtherance
- Glacier's Laboratory
- Godmode Achieved
- Heaven's Call
- Hex Cards
- Insane Pain Mod
- Inscryption Card Pack
- Isaac's Limbus
- Job
- Joseph
- Juglans Box
- Kicks and Giggles
- Lazy MattPack
- Library Expanded
- Lost and Forgotten
- Magic Expanded
- Malware & Spam
- Martha of Bethany
- Mastema
- Me's Very Rocky Collection
- Minmaxers Anonymous
- Mollith's Item Bunch
- More Penny Trinkets
- More Unus Cards
- Neapolitan Pack
- Pail O Items
- Painted Paths
- PJJ & Niro's Collection
- Pop Pack
- Potato Packs
- Preyn's Collection
- Red Baby
- Repentance Negative
- Repentance Plus
- Reshaken
- Restored Mods
- Revelations
- Reverie
- Reverie: Make Good Omissions
- Road to Enlightenment
- Sacred Dreams
- Samael
- Sewing Machine
- Shattered Symbols
- Sweet Halloween
- TBOI Ascension
- TBOI Otherside
- TBoI: Regambled
- The Bimbing of AIsaac
- The binding of Neuro-sama
- The Forbidden Suits
- The Gauntlet
- The Miles Mod
- The Punished
- The Serpent
- The Sheriff
- The Sheriff: Most Wanted
- Virtue Items
- Warp Zone
28 more currently being worked on!
- Add your mod
- To the GuruWiki
▾Table of Contents▾
Branch of Knowledge item
Branch of Knowledge is an unlockable active item in Isaac's Limbus, a mod for The Binding of Isaac.
Description
Isaac slashes all enemies in range with a large axe that deals damage equal to DamageStat × 4.
Inflict 12 Rupture Potency to enemies hit by the slash.
If Isaac has Soul Hearts, lose all Soul Hearts. Gain (# of Soul Hearts lost) damage for the next 4 rooms.
If Isaac has no Soul Hearts, gain 1 Soul Heart, and a wisp.
How to unlock?
Unlock 
Sinclair.
Item pools
Branch of Knowledge can be found in the following item pools:
| Name | Weight |
|---|---|
| Treasure Room |
0.6/1.0
|
| Devil Room |
0.6/1.0
|
| Curse Room |
0.6/1.0
|
| Secret Room |
0.6/1.0
|
| Greed Shop |
0.6/1.0
|
| Greed Devil Room |
0.6/1.0
|
| Greed Secret Room |
0.6/1.0
|
| Old Chest |
0.6/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| offensive | Can appear for  Tainted Lost. |
External links
- Download Isaac's Limbus from the Steam Workshop.
Rusted Hilt 
Ritualist's Right 
Thrashing to Hatch 
Someone's Device 
Manor Shaped Music Box 
Bell of Truth