Challenges

Name	Character	Starting items	Disabled rooms	Curse filters	Additional notes	End goal	Unlock condition	Reward
1. [AIsaac]Strict Supervision	AIsaac	Lil' Kami (inherent)	-	-	Lil' Kami has an altered effect: Always follows AIsaac. Doesn't affect enemies, instead affects AIsaac, his tears, and familiars. Has only half a second cooldown between changing his sign, and the sign stays for 2 seconds. Exploding a bomb will disable Lil' Kami's sign for 15 seconds. Exploding another one will cancel out the effect of the previous one.	Mom's Heart	-	Kami's Whip
2. [AIsaac]Streamover	AIsaac	Bent Antenna	-		+0.75 damage. AIsaac has an area of light surrounding him. The light decreases over time. Enemies outside the light area are slowed down. When the light is fully gone, the game is over. To increase the light, clear hostile rooms. The amount of light AIsaac gets depends on the amount of total health the enemies have, boss rooms always gives 60 seconds. Dying during Kami's Shadow fight unlocks Practice Mode Bent Antenna has an altered effect: Behaves as a pocket item with completely altered effects and requiring only 3 charges. Makes the light zone around Isaac visually bigger, prevents the light level from decreasing or increasing for the current room. If used on the sixth floor, just breaks itself. If Practice Mode (or Practice Mode+) is unlocked, using this item in the very first starting room will teleport AIsaac to the last floor and make him survive Kami's Shadow's attacks for 60 seconds. Completing Practice Mode+ unlocks Kamijoan	Kami's Shadow	-	Lobotomy Practice Mode+
3. [AIsaac]Static Seed	AIsaac	Forget Me Now (pocket, unlimited use)	-		+0.25 damage. The floor and room layout are always the same. Rooms consist of various puzzles with special mechanics like Puzzle Tiles, Colored Keys, Trigger Flames etc. Some rooms contain Reward Tokens that increase AIsaac's Reward by 1. Taking damage decrease Reward by 0.5 (limit -5 per floor). Using Forget Me Now will reset the floor and decrease Reward by 2 (limit -5 per floor). Reward can be used to buy pickups and items to skip certain puzzles or make them easier. Collecting 25 Reward Tokens and bringing 20 Reward to the last floor unlocks The Reward. Reaching the last floor under 7 minutes 30 seconds unlocks Runner's Watch. Reaching the last floor with -40 Reward unlocks Oxidized Penny and Corroded Nickel.	The Corroded	-	Vending Machine
4. [AIsaac]Doorphobia	AIsaac	Book of Secrets 9 Volt AAA Battery (gulped) NO! (gulped)	-		All doors are replaced with door illusions that look the same. The only exceptions are Curse Room doors and Boss Room doors. Fake doors spawn at all places where a regular door could have spawned. Entering a fake door could have one of a few various negative effects like teleport to the starting room, all stats down for the rest of the floor, Cursed Eye for 30 seconds etc. After entering too many fake doors, Pumkin will appear acd chase AIsaac for the rest of the floor. While Pumkin is present, fake doors vanish when approached. Book of Secrets effect is altered: Reveals all fake doors in the current room. Fake doors won't appear in this room anymore.	Mom	-	Cursed Doorknob