Poise is a system in Basement Moon, a mod for The Binding of Isaac.
A keyword with Potency and Count, each capped at 99. Potency appears to the left of its icon and Count to the right. Gaining only one value also supplies a minimum of 1 of the other value.
Every 3 seconds while Isaac has Poise, a (Potency × 5)% roll is made. Success consumes 1 Count and grants +20% Damage for 3 seconds.
At 20 Potency or more, every roll succeeds. Repeated successes refresh the bonus rather than stacking it.
Poise ends when Count reaches 0. The final Damage bonus lasts until its 3 seconds expire.