Rupture is a system in Basement Moon, a mod for The Binding of Isaac.
A keyword with Potency and Count, each capped at 99. Potency appears to the left of its icon and Count to the right. Gaining only one value also supplies a minimum of 1 of the other value.
An afflicted enemy accumulates damage received. When the total reaches 50, it takes extra damage equal to Rupture Potency and loses 1 Count.
The accumulated damage resets to 0, discarding any excess. A single damage event can trigger Rupture only once. Rupture's own damage is not added to its counter.
If Isaac is afflicted with Rupture, taking damage instead triggers (Potency / 9, rounded up) half-Hearts of extra damage and consumes 1 Count.
Rupture ends when Count reaches 0.