Handcuffs is a trinket in Curiosity Crate, a mod for The Binding of Isaac.
Mom's Hand and Mom's Dead Hand enemies turn into 2-4 friendly Blue Spiders or Blue Flies.
The following special synergies and interactions for Handcuffs have been documented.
Mod | Item | Synergy |
---|---|---|
--- | Trinket multipliers | Doubles the amount of spawned Blue Spiders and Blue Flies. |
* Note that not all possible synergies and interactions are listed here.