▾Table of Contents▾
Placebo item
Placebo is an active item in The Binding of Isaac, added in the Afterbirth DLC.
Description
Copies the effect of Isaac's currently held pill without consuming it.
The recharge time depends on the last used pill. Check the specific pill page for more details.
Note
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.
Item pools
Placebo can be found in the following item pools:
| Name | Weight |
|---|---|
| Shop |
1.0/1.0
|
| Secret Room |
1.0/1.0
|
| Greed Shop |
1.0/1.0
|
| Greed Secret Room |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| offensive | Can appear for  Tainted Lost. |
| nocantrip | Not available as card effects during the Cantripped! challenge. |
Special synergies
The following special synergies and interactions for Placebo have been documented.
| Mod | Item | Synergy |
|---|---|---|
| --- | Book of Virtues | Spawns white wisps in the middle ring that spawn pills when destroyed. |
* Note that not all possible synergies and interactions are listed here.
Internal item description
Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.
Placebo
• Triggers the effect of the pill held without consuming it
• Variable charge based on the last pill copied
• Abyss: x1 locust .75x Isaac's damage
• Book of Virtues: x1 middle wisp - 2 hp - 3 damage
• Book of Virtues: Spawns a pill when killed
External links
- Check out the item description on the external Isaac Wiki.
Synthoil 
A Snack 
Diplopia 
Wooden Nickel 
Toxic Shock 
Mega Bean