Chaos is a passive item in The Binding of Isaac, added in the Afterbirth DLC.

On pickupDrops 1-6 random pickups around Isaac.

While heldCauses items to be chosen from random item pools.

Fixed item drops that ignore the current room's item pool are not affected. Such examples include Cube of Meat after defeating a Harbinger, The Small Rock after breaking a Tinted Rock, etc.

Each pool has a different weight (chance to be selected) based on the number of items inside it, with pools having more items being much more likely to be chosen than smaller pools.

Cannot mix up pools between Greed Mode and the normal game.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

Chaos can be found in the following item pools:

The following tags are applied to this item:

The following special synergies and interactions for Chaos have been documented.

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Chaos

• Spawns 1-6 pickups
• All item pedestals draw from random item pools
• Abyss: x1 glitched locust 1.5x Isaac's damage

• Check out the item description on the external Isaac Wiki.