Curse of the Giant! is a curse in The Binding of Isaac, added in the Repentance DLC.
Merges normal-sized rooms into large rooms.
Currently not achievable naturally in game, and not fully working properly.
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this curse for the previous Repentance version, check this page instead.