A Card Against Humanity - The Binding of Isaac

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A Card Against Humanity is an unlockable consumable in The Binding of Isaac.

Fills the entire room with poop.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this consumable for the previous Repentance version, check this page instead.

Complete challenge #12: When Life Gives You Lemons.

The following special synergies and interactions for A Card Against Humanity have been documented.

Mod	Item	Synergy
---	Tarot Cloth	No effect.
---	Blank Card	Mimic recharge time: 6 rooms

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

A Card Against Humanity

• Fills every floor tile with poop
• Blank Card: Recharge 6

The following sounds are related to this consumable.