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Immaculate Conception item
Immaculate Conception is an unlockable passive item in The Binding of Isaac, added in the Afterbirth DLC.
Description
Grants a permanent angelic familiar and spawns a 
Soul Heart for every 15 hearts picked up.
Possible familiars include:
• Holy Water
• Guardian Angel
• Sworn Protector
• The Relic
• Seraphim
Only one of each familiar can spawn. After all of them have spawned, a Soul Heart will continue to drop after every 15 hearts collected.
Any heart pickups count except for 
Gold Hearts and 
Blended Hearts.
Note
This page shows information as of the latest Repentance release.
To see latest up-to date information about this item for the new Repentance+ (Online Co-op) DLC, check this page instead.
How to unlock?
Complete Boss Rush as 
Lilith.
Item pools
Immaculate Conception can be found in the following item pools:
| Name | Weight |
|---|---|
| Angel Room |
1.0/1.0
|
| Greed Angel Room |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| nolostbr | Unavailable for  The Lost after obtaining  Birthright. |
| summonable | Can be summoned via  Lemegeton. |
External links
- Check out the item description on the external Isaac Wiki.
Evil Eye 
Lusty Blood 
Cambion Conception 
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Deep Pockets