Anima Sola is an unlockable active item in The Binding of Isaac, added in the Repentance DLC.

Chains down the nearest enemy, completely preventing them from acting for 5 seconds.

Using the item again, even if not fully charged, will release the enemy immediately.

The effect also works on enemies that are invulnerable.

When playing as Tainted Jacob The chain will always be set on Dark Esau, if he is present. Releasing Dark Esau will immediately cause him to charge at Tainted Jacob.

Dark Esau deals no contact damage to Jacob while chained down.

If used in a room without any enemies before Dark Esau has spawned, it will immediately summon him without wasting a charge.

This page shows information as of the latest Repentance release.
To see latest up-to date information about this item for the new Repentance+ (Online Co-op) DLC, check this page instead.

Defeat Delirium as Tainted Jacob.

Anima Sola can be found in the following item pools:

The following tags are applied to this item:

The following special synergies and interactions for Anima Sola have been documented.

* Note that not all possible synergies and interactions are listed here.

• Check out the item description on the external Isaac Wiki.