Curse of Creation is a curse in Preyn's Collection, a mod for The Binding of Isaac. It is part of the Cursed Collection submod.
Breaking rocks has a 65% chance to make them re-appear.
Obstacles have a 20% chance of turning into Spiked Rocks and a 5% chance of turning into Fool's Gold or Tinted Rocks.
Tinted Rocks, Super Secret Rocks, and Fool's Gold rocks have a 90% chance of turning into Spiked Rocks.
If Isaac gets stuck due to this effect, he will be moved to a nearby position or teleported to a random door.
Part of the Cursed Collection mod.