Infestation 2 is a passive item in The Binding of Isaac.

Spawns a friendly Blue Spider upon killing an enemy.

Blue Spiders themselves cannot spawn more Blue Spiders when killing enemies.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

This item contributes towards the Spider Baby transformation. Collecting 3 items from this set will spawn a spider familiar that applies random status effects when it comes in contact with enemies.

Infestation 2 can be found in the following item pools:

The following tags are applied to this item:

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Infestation 2

• Killing an enemy spawns a blue spider
• Abyss: x1 locust 1.5x Isaac's damage

• Check out the item description on the external Isaac Wiki.