E. Coli is a passive item in The Binding of Isaac.

Grants Isaac the ability to turn non-boss enemies into poop by touching them.

Poops spawned this way can yield pickups when destroyed.

Increases the chance of poops dropping hearts.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

This item contributes towards the Oh Crap transformation. Collecting 3 items from this set will grant Isaac the ability to heal half a heart by destroying poop piles.

E. Coli can be found in the following item pools:

The following tags are applied to this item:

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

E. Coli

• Touching enemies turns them into poop
• Abyss: x1 poop locust .5x Isaac's damage

• Check out the item description on the external Isaac Wiki.