Large Zit is a passive item in The Binding of Isaac, added in the Afterbirth+ DLC.

Grants Isaac a chance to fire a creep shot alongside his tears that deals double damage, slows enemies and leaves a short trail of slowing white creep on the ground.

Fires a creep shot in a random direction upon taking damage.

The chance to fire a creep shot is not affected by luck.

Creep shots inherit Isaac's shot speed, but not his tear effects.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

Large Zit can be found in the following item pools:

The following tags are applied to this item:

The following special synergies and interactions for Large Zit have been documented.

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Large Zit

• Chance to fire a zit shot that deals 2x Isaac's damage and spawns pools of slowing white creep
• Taking damage also launches a zit shot in a random direction
• Abyss: x1 slowing locust .75x Isaac's damage

• Check out the item description on the external Isaac Wiki.