Soul of Cain is an unlockable consumable in The Binding of Isaac, added in the Repentance DLC.
Opens all doors in the room, and creates Red Key rooms on all valid walls.
Will destroy the entrance to the Mirrored World in Downpour / Dross II.
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this consumable for the previous Repentance version, check this page instead.
Defeat Hush and complete Boss Rush as Tainted Cain.
The following special synergies and interactions for Soul of Cain have been documented.
Mod | Item | Synergy |
---|---|---|
--- | Clear Rune | Mimic recharge time: 6 rooms |
* Note that not all possible synergies and interactions are listed here.
The following sounds are related to this consumable.