Clear Rune is an unlockable active item in The Binding of Isaac, added in the Repentance DLC.
On pickupDrops a random rune.
On useCopies the effect of Isaac's currently held rune or soul stone.
The recharge time depends on the last copied rune or soul stone. Check the page of each rune or soul stone for more details.
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.
Complete challenge #30: The Guardian.
Clear Rune can be found in the following item pools:
Name | Weight |
---|---|
Secret Room |
1.0/1.0
|
Greed Secret Room |
1.0/1.0
|
Crane Game |
1.0/1.0
|
The following tags are applied to this item:
Id | Description |
---|---|
offensive | Can appear for ![]() |
nocantrip | Not available as card effects during the Cantripped! challenge. |
The following special synergies and interactions for Clear Rune have been documented.
Mod | Item | Synergy |
---|---|---|
--- | Book of Virtues | Spawns purple glowing wisps in the middle ring. The wisps spawn runes/soul stones when destroyed. Enemies killed by the wisps' tears have a 15% chance to drop a rune/soul stone. |
* Note that not all possible synergies and interactions are listed here.