Locust of War is an unlockable trinket in The Binding of Isaac, added in the Afterbirth+ DLC.

Upon entering an unexplored room, spawns a Red Locust that detonates upon impact with enemies, dealing 2x Isaac's damage for the impact, and 60 for the explosion.

The explosion synergizes with Isaac's bomb effects.

The explosion can damage Isaac and the environment.

Has a 1% chance of being dropped upon defeating War.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this trinket for the previous Repentance version, check this page instead.

Defeat Isaac as Apollyon.

The following special synergies and interactions for Locust of War have been documented.

* Note that not all possible synergies and interactions are listed here.

• Check out the trinket description on the external Isaac Wiki.