Locust of War is an unlockable trinket in The Binding of Isaac, added in the Afterbirth+ DLC.

Upon entering an unexplored room, spawns a Red Locust that detonates upon impact with enemies, dealing 2x Isaac's damage for the impact, and 60 for the explosion.

The explosion synergizes with Isaac's bomb effects.

The explosion can damage Isaac and the environment.

Has a 1% chance of being dropped upon defeating War.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this trinket for the previous Repentance version, check this page instead.

Defeat Isaac as Apollyon.

The following special synergies and interactions for Locust of War have been documented.

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Locust of War

• Spawns an explosive locust upon entering a new combat room
• Golden Trinket (without Mom's Box): Spawns 2 explosive locusts upon entering a new combat room
• Mom's Box: Spawns 2 explosive locusts upon entering a new combat room
• Mom's Box + Golden Trinket: Spawns 3 explosive locusts upon entering a new combat room

• Check out the trinket description on the external Isaac Wiki.