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Mama Mega! item
Mama Mega! is an active item in The Binding of Isaac, added in the Afterbirth+ DLC.
Description
Destroys all obstacles, machines, beggars, etc and deals 200 damage to every enemy. This effect is applied upon entering each room for the entire floor.
It will also open up any doors in the rooms, including Secret Room and Super Secret Room entrances.
Will blow up the 
Donation Machine as well, rendering it unusable for the rest of the run.
Opens the door to Boss Rush and Hush even after the time limit has expired.
If Isaac has a 
Golden Bomb, it will change Mama Mega's sprite on the HUD to a golden one, and using Mama Mega will consume the Golden Bomb, allowing Mama Mega to be used again.
Note
This page shows information as of the latest Repentance release.
To see latest up-to date information about this item for the new Repentance+ (Online Co-op) DLC, check this page instead.
Item pools
Mama Mega! can be found in the following item pools:
| Name | Weight |
|---|---|
| Shop |
0.5/1.0
|
| Greed Shop |
0.5/1.0
|
| Bomb Bum |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| offensive | Can appear for  Tainted Lost. |
Special synergies
The following special synergies and interactions for Mama Mega! have been documented.
| Mod | Item | Synergy |
|---|---|---|
| --- | Book of Virtues | Spawns 8 wisps in the middle ring that summon  Golden Troll Bombs when destroyed. |
* Note that not all possible synergies and interactions are listed here.
External links
- Check out the item description on the external Isaac Wiki.
Compost 
Dataminer 
Clicker 
Wait What? 
Crooked Penny 
Dull Razor