Blood of the abyss is a passive item in Preyn's Collection, a mod for The Binding of Isaac. It is part of the Toybox Collection submod.

On pickup Converts all of Isaac's Red Heart containers into Soul Hearts.

While held Negates 3 instances of damage on every floor.

The blue flies on the costume represent the number of hits Isaac can take before the shield breaks.

Each copy grants +3 additional shields.

Part of the Toybox Collection mod.

Blood of the abyss can be found in the following item pools:

This item is a reference to the game Hollow Knight. Resembling the Lifeblood mechanic.

• Check out the item description on the mod's external Wiki.
• Download Preyn's Collection from the Steam Workshop.