Jeffrey's Shackle is an unlockable trinket in Damnation, a mod for The Binding of Isaac.

-1/(2+TrinketMultiplier) damage multiplier.

Isaac can trigger room-clear effect by killing 1 enemy.

Defeat Mother as Tainted Juzzle.

The following special synergies and interactions for Jeffrey's Shackle have been documented.

* Note that not all possible synergies and interactions are listed here.

This trinket references to Goatman (Jeffrey), the hunter from Identity V.
The sprite of this trinket is from Goatman's weapon.
The effect of this trinket references the fact that Goatman can only deals halved damage outside of his cage, and dealing damage inside a cage will remove the cage.

• Download Damnation from the Steam Workshop.