Guppy's Paw - The Binding of Isaac

▾Table of Contents▾

Guppy's Paw is an active item in The Binding of Isaac.

+3 Soul Hearts.
-1 Red Heart container.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

This item contributes towards the Guppy transformation. Collecting 3 items from this set will grant Isaac flight and spawn a Blue Fly 66% of the time when a tear hits an enemy.

Guppy's Paw can be found in the following item pools:

Name	Weight
Devil Room	1.0/1.0
Red Chest	1.0/1.0
Curse Room	1.0/1.0
Greed Curse Room	1.0/1.0
Greed Devil Room	1.0/1.0

The following tags are applied to this item:

Id	Description
nolostbr	Unavailable for The Lost after obtaining Birthright.
dead	Contributes towards unlocking The Parasite.
guppy	Contributes towards the Guppy transformation.

The following special synergies and interactions for Guppy's Paw have been documented.

Mod	Item	Synergy
---	Book of Virtues	Spawns 3 wisps in the middle ring for every red heart container consumed, in addition to granting soul hearts. The wisps have a large amount of health.
---	The Book of Belial combined with Judas' Birthright	Grants +0.5 damage.

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Guppy's Paw

• Permanently removes 1 HP to grant 3 soul hearts
• Abyss: x1 locust 1.5x Isaac's damage
• Book of Virtues: x3 middle wisps - 20 hp - 3.5 damage