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Zodiac item
Zodiac is an unlockable passive item in The Binding of Isaac, added in the Afterbirth DLC.
Description
Grants the effects of a random Zodiac item each floor.
Note
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.
How to unlock?
Defeat Ultra Greed as The Lost.
Item pools
Zodiac can be found in the following item pools:
| Name | Weight |
|---|---|
| Treasure Room |
1.0/1.0
|
| Greed Treasure Room |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| summonable | Can be summoned via  Lemegeton. |
| offensive | Can appear for  Tainted Lost. |
| stars | Contributes towards unlocking Planetariums. |
Internal item description
Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.
Zodiac
• Grants 1 random Zodiac item effect
• The granted Zodiac effect is rerolled at the start of each floor
• Abyss: x1 locust .75x Isaac's damage
External links
- Check out the item description on the external Isaac Wiki.
Rune Bag 
Seraphim 
Betrayal 
Serpent's Kiss 
Marked 
Tech X