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Serpent's Kiss item
Serpent's Kiss is an unlockable passive item in The Binding of Isaac, added in the Afterbirth DLC.
Description
Grants a 15% chance to fire poison tears that deal a total of 2x Isaac's damage.
Inflicts poison on enemies that make contact with Isaac. The poison will tick 6 times, each tick dealing Isaac's amount of damage.
Enemies that were inflicted with poison via contact damage have a 20% chance to drop a 
Black Heart.
Note
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.
How to unlock?
Defeat Satan as 
Lilith.
Item pools
Serpent's Kiss can be found in the following item pools:
| Name | Weight |
|---|---|
| Treasure Room |
1.0/1.0
|
| Greed Treasure Room |
1.0/1.0
|
Tags
The following tags are applied to this item:
| Id | Description |
|---|---|
| summonable | Can be summoned via  Lemegeton. |
| offensive | Can appear for  Tainted Lost. |
Special synergies
The following special synergies and interactions for Serpent's Kiss have been documented.
| Mod | Item | Synergy |
|---|---|---|
| --- | Abyss | Spawns a green locust that has a chance to poison enemies. |
* Note that not all possible synergies and interactions are listed here.
External links
- Check out the item description on the external Isaac Wiki.
Seraphim 
Betrayal 
Zodiac 
Marked 
Tech X 
Ventricle Razor