IBS is an unlockable passive item in The Binding of Isaac, added in the Repentance DLC.

After dealing enough damage to enemies, Isaac begins to flash red. Once this happens, releasing the fire button activates one of Tainted ???'s unique poop abilities.

IBS cannot activate if Isaac is currently holding a poop.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

Defeat Delirium as Tainted ???.

This item contributes towards the Oh Crap transformation. Collecting 3 items from this set will grant Isaac the ability to heal half a heart by destroying poop piles.

IBS can be found in the following item pools:

The following tags are applied to this item:

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

IBS

• Chance when damaging an enemy to glow red and gain a throwable poop with one of several effects that can damage enemies
• Release attack buttons to wield the poop, then press an attack button to throw it
• Abyss: x1 poop locust .5x Isaac's damage

• Check out the item description on the external Isaac Wiki.