Onan's Streak is an unlockable challenge in The Binding of Isaac, added in the Afterbirth DLC.
This page shows information as of the latest Repentance release.
To see latest up-to date information about this challenge for the new Repentance+ (Online Co-op) DLC, check this page instead.
Note: this list does not include characters' default starting items.
+2 damage.
Missing a shot deals half a heart of damage to Judas.
The following is unlocked for completing the Onan's Streak challenge: Kidney Stone
Unlock Judas and It Lives!