Infestation is a passive item in The Binding of Isaac.

Spawns 2-6 Blue Flies upon taking damage.

Has a 1% chance of being dropped upon defeating The Husk.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.

This item contributes towards the Beelzebub transformation. Collecting 3 items from this set will grant Isaac flight, converts small enemy flies into Blue Flies, and permanently charms larger enemy flies.

Infestation can be found in the following item pools:

The following tags are applied to this item:

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Infestation

• Spawn 2-6 blue flies whenever Isaac takes damage
• Abyss: x1 locust .5x Isaac's damage

• Check out the item description on the external Isaac Wiki.