Soul of Apollyon is an unlockable consumable in The Binding of Isaac, added in the Repentance DLC.

Spawns 15 random 7 Seals locusts.

This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this consumable for the previous Repentance version, check this page instead.

Defeat Hush and complete Boss Rush as Tainted Apollyon.

The following special synergies and interactions for Soul of Apollyon have been documented.

* Note that not all possible synergies and interactions are listed here.

Below is the Internal Item Description as shown in-game.
Note that some stat changes are not displayed here. Please see the main description for the full effects.

Soul of Apollyon

• Spawns 15 random locusts
• Clear Rune: Recharge 6

The following sounds are related to this consumable.

• Check out the consumable description on the external Isaac Wiki.