Insane Mode - The Binding of Isaac

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Insane Mode is an unlockable difficulty in Community Remix, a mod for The Binding of Isaac.

This is a gamemode that can be selected on the character menu.

Isaac's heart cap is reduced to 6 hearts.
All heart pickups that would be full hearts are now halved.
Regular rooms and treasure rooms have a chance to be Hexed.
Bomb pickups have a chance to be replaced with a Troll Bomb when touched.
Pacers and Gushers leave red creep on the floor.

Beating Mom's Heart on Insane mode will reward Isaac with an Insane Pin, which will be displayed in the character menu on top of the post-it note for the character it has been beat with. It will also unlock that character's Insane mode unlock.

Beating Mom's Heart as any character will also unlock Insane Pendant and Shrunken Head.

Defeat Mom's Heart 5 times.

The following special synergies and interactions for Insane Mode have been documented.

Mod	Item	Synergy
---	Isaac	Unlocks Akedah.
---	Magdalene	Unlocks Communion Wine.
---	Cain	Unlocks Lucky Charm.
---	Judas	Unlocks Ceremonial Blade.
---	???	Unlocks Bygone.
---	Eve	Unlocks Occam's Razor.
---	Samson	Unlocks Donkey's Jawbone.
---	Azazel	Unlocks Goat Heart.
---	Lazarus	Unlocks Misericorde.
---	Eden	Unlocks _NULL.
---	The Lost	Unlocks Sanctified Heart.
---	Lilith	Unlocks Dark Penny.
---	Keeper	Unlocks Bum Mug.
---	Apollyon	Unlocks Cloud Nine.
---	The Forgotten	Heart cap reduced to 3. Unlocks Hand-Me-Downs.
---	Bethany	Unlocks Beth's Virtue.
---	Jacob and Esau	Unlocks Twin Candles.
Community Remix	Adam	Unlocks Ophiuchus.
Community Remix	Abel	Unlocks Gacha Bombs.