[Epiph] Overwhelming Odds is a challenge in Epiphany, a mod for The Binding of Isaac.
Note: this list does not include characters' default starting items.
Tarnished Isaac starts with 12 slots.
All items are selected from random pools as if holding Chaos.
Chance Cube is automatically used on occasion without consuming any charges.
Soul of the Lost is triggered upon entering any Boss Room, and Crooked Penny in Treasure Rooms.
The following is unlocked for completing the [Epiph] Overwhelming Odds challenge: Chance Cube