Pandora's Box is an unlockable active item in The Binding of Isaac.
Spawns specific pickups or items depending on the floor it was used on:
Floor | Reward |
---|---|
Basement I | 2 ![]() |
Basement II | 2 Bombs and 2 ![]() |
Caves I | 1 Boss item |
Caves II | 1 Boss item and 2 ![]() |
Depths I | 4 ![]() |
Depths II | 20 ![]() |
Womb I | 2 Boss items |
Womb II | The Bible |
??? (Blue Womb) | nothing |
Sheol | 1 Devil Room item and 1 ![]() |
Cathedral | 1 Angel Room item and 1 ![]() |
Dark Room | nothing; unlocks Moving Box |
Chest | 1 ![]() |
The Void | nothing |
Home | Red Key |
The Shop / Ultra Greed | 1 ![]() |
This page shows the latest information as of the new Repentance+ (Online Co-op) DLC.
To see information about this item for the previous Repentance version, check this page instead.
Defeat The Lamb as Lazarus.
Pandora's Box can be found in the following item pools:
Name | Weight |
---|---|
Shop |
1.0/1.0
|
Red Chest |
1.0/1.0
|
Greed Shop |
1.0/1.0
|
The following tags are applied to this item:
Id | Description |
---|---|
offensive | Can appear for ![]() |
The following special synergies and interactions for Pandora's Box have been documented.
Mod | Item | Synergy |
---|---|---|
--- | Book of Virtues | Spawns multiple regular wisps based on the current floor - 1. This means that no wisps will be spawned on the first floor. |
--- | The Book of Belial combined with Judas' Birthright | In addition to the regular payout, also spawns one of the following familiars: ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
* Note that not all possible synergies and interactions are listed here.
The following sounds are related to this item.